Post-Transplant Cyclophosphamide Is Associated with Early Expansion of Regulatory T cells and Monocytic Myeloid-Derived Suppressor Cells after Allogeneic Hematopoietic Cell Transplantation | Synapse
March 3, 2026
Post-Transplant Cyclophosphamide Is Associated with Early Expansion of Regulatory T cells and Monocytic Myeloid-Derived Suppressor Cells after Allogeneic Hematopoietic Cell Transplantation
Key Points
Regulatory T cells and monocytic myeloid-derived suppressor cells expand significantly after treatment.
Expansion of regulatory T cells occurs within days of cyclophosphamide administration.
Observational analysis highlighting immunological changes following transplantation and cyclophosphamide.
These findings may enhance strategies for improving tolerance in transplant settings.