Genomic analysis of a multidrug-resistant monophasic Salmonella Typhimurium from Chinese beef harboring a novel mcr-1-bearing IncHI2-IncHI2A plasmid

Key Points

• Genomic analysis shows the presence of a novel mcr-1-bearing plasmid in multidrug-resistant Salmonella Typhimurium.
• The novel plasmid was identified in a sample from Chinese beef, indicating foodborne risks.
• Analysis focused on the genetic mechanisms of resistance, especially the mcr-1 gene associated with colistin resistance.
• The findings emphasize the need for enhanced monitoring of food sources to prevent the spread of antibiotic resistance.