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Efficacy of Allogenic Stem Cell Transplant in KMT2A Partial Tandem Duplication ( -PTD) Myeloid Neoplasms | Synapse
March 3, 2026
Efficacy of Allogenic Stem Cell Transplant in KMT2A Partial Tandem Duplication ( -PTD) Myeloid Neoplasms
PA
Peter Abdelmessieh
BS
Bhaumik Shah
Fox Chase Cancer Center
YS
Yuliya Shestovska
Fox Chase Cancer Center
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Key Points
Efficacy of allogenic stem cell transplant shows promise in treating myeloid neoplasms associated with KMT2A alterations.
Patients with KMT2A partial tandem duplication may respond positively to this transplant approach, enhancing survival.
Assessment based on patient records indicates significant outcomes following intervention over a specified follow-up period.
Findings highlight the need for further exploration into stem cell interventions for specific myeloid neoplasms.
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Cite This Study
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Abdelmessieh et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760b9c6e9836116a2dbb0
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.159