Elevated circulating CD10−granulocytic myeloid-derived suppressor cells correlate with disease activity and poor prognosis in patients with diffuse large B-cell lymphoma

Key Points

• Elevated CD10−granulocytic myeloid-derived suppressor cells correlate with poor prognosis in diffuse large B-cell lymphoma.
• A significant relationship was observed between circulating CD10−cells and disease activity, affecting patient outcomes.
• Using a cohort analysis, the study examined prognostic factors related to CD10−granulocytic myeloid-derived suppressor cells in patients with lymphoma.
• Findings suggest that targeting these cells may improve treatment approaches for diffuse large B-cell lymphoma.