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In the Post-Transplant Cyclophosphamide (PTCy) Era, Overall Survival (OS) By Donor Differs By Recipient and Donor Age and Race/Ethnicity | Synapse
March 3, 2026
In the Post-Transplant Cyclophosphamide (PTCy) Era, Overall Survival (OS) By Donor Differs By Recipient and Donor Age and Race/Ethnicity
MH
Megan Herr
NN
Nisha M. Nair
SH
Shernan G. Holtan
Roswell Park Comprehensive Cancer Center
See all
Key Points
Overall survival is influenced by both donor and recipient characteristics, highlighting the complexity of transplant outcomes.
Key evidence indicates survival rates differ significantly based on donor age and race/ethnicity, emphasizing disparities in care.
Analysis of transplant outcomes demonstrates variations in survival linked to specific donor-recipient age pairings and ethnic backgrounds.
The findings call for careful consideration of donor characteristics in transplant protocols, as they likely affect patient outcomes.
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Herr et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760c4c6e9836116a2dd2d
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.955