Substance P involvement in the interaction between Streptococcus mutans and human aortic endothelial cells

Key Points

• Inflammation is heightened by substance P in conjunction with Streptococcus mutans.
• The interaction was noted to increase cytokine levels impacting endothelial function.
• Bioassays confirmed the role of Streptococcus mutans in stimulating endothelial cells.
• This work implies that targeting substance P may offer new therapeutic strategies.