Value of “true” leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting | Synapse
March 3, 2026Open Access
Value of “true” leukocytosis formula in determining total knee arthroplasty prosthetic joint infection in the community hospital setting
Key Points
The proposed true leukocytosis formula does not aid in differentiating prosthetic joint infection effectively.
Despite applying the formula, there was little variance in the ICM score among patients evaluated during the study.
Observational analysis at community hospitals evaluated treatment decision accuracy in joint surgeries using the formula.
Further assessment is needed to find reliable methods for diagnosing infections in knee arthroplasty patients.
Abstract
Given the lack of variance in ICM score following the proposed correction formula, it appears that the proposed "true leukocytosis" formula is not a useful adjuvant in treatment decision making.