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Donor Chimerism at Day +90 Predicts Better Survival Outcomes Among Allogeneic Hematopoietic Cell Transplantation Recipients Receiving Myeloablative Conditioning | Synapse
March 3, 2026
Donor Chimerism at Day +90 Predicts Better Survival Outcomes Among Allogeneic Hematopoietic Cell Transplantation Recipients Receiving Myeloablative Conditioning
SJ
Sara Jubas
University of North Carolina at Chapel Hill
KC
Kieran D. Collins
HL
Hsuan-Hui Liu
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Key Points
Improved survival outcomes associate strongly with high levels of donor chimerism.
The analysis indicated that donor chimerism was a predictor of survival at Day +90 post-transplant.
Assessment of donor chimerism occurs at the 90-day mark after myeloablative conditioning.
Findings suggest donor chimerism may serve as an important biomarker for transplantation success.
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Jubas et al. (Sun,) studied this question.
synapsesocial.com/papers/69a760d5c6e9836116a2df62
https://doi.org/https://doi.org/10.1016/j.jtct.2025.12.579
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