Design of hyaluronic acid-based glutathione-gelatin-collagen-laminin loaded 3D bioactive transdermal tissue scaffold: Determination of biocompatibility, antimicrobial and ROS

Key Points

• Biocompatibility and antimicrobial properties of the 3D scaffold were assessed comprehensively, indicating positive outcomes.
• The scaffold incorporates hyaluronic acid, gelatin, collagen, and laminin, promoting cellular interaction.
• Evaluation included measurements of reactive oxygen species (ROS) production, providing insights into oxidative stress.
• This work supports the potential of bioactive materials for enhancing transdermal therapeutic delivery systems.