Exploring the kidney-protective potential of traditional Zhuang medicine 'Yingbupu': Insights from serum metabolomics, network pharmacology, and experimental validation | Synapse
March 3, 2026Open Access
Exploring the kidney-protective potential of traditional Zhuang medicine 'Yingbupu': Insights from serum metabolomics, network pharmacology, and experimental validation
Key Points
The renoprotective effect indicates significant potential for kidney health improvement.
Key evidence shows that Yingbupu effectively reverses Wnt/β-catenin pathway activation.
Assessment using serum metabolomics and network pharmacology approaches leads to insights about effectiveness.
Findings may indicate new treatment avenues for kidney-related conditions, necessitating further investigation.
Abstract
The renoprotective effect of YBP can be attributed to its ability to effectively reverse the abnormal activation of Wnt/β-catenin pathway.