Non-invasive MRI biomarkers for assessment of neoadjuvant chemotherapy response in osteosarcoma: Current techniques and clinical perspectives

Key Points

• Non-invasive MRI biomarkers enhance evaluation of tumor response during neoadjuvant chemotherapy in osteosarcoma.
• The incorporation of MRI innovations may improve treatment personalization through better response monitoring.
• Assessment involved a variety of current MRI techniques across multiple clinical settings for osteosarcoma.
• Challenges in standardization and inter-observer variability highlight the need for more consensus in clinical practice.