Caffeic acid phenethyl ester and its micro- and nanoformulations with anticancer activities

Key Points

• Caffeic acid phenethyl ester exhibits significant anticancer activities against various cancer cell lines, promoting apoptosis.
• The study highlights the enhanced effects of both micro- and nanoformulations on cancer cell growth inhibition, with up to 70% reduction noted.
• Assessment using biological assays demonstrated that both formulations target multiple cancer pathways, improving efficacy.
• This research underscores the potential of caffeic acid phenethyl ester formulations in anticancer therapies, calling for further clinical studies.