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March 3, 2026
Sodium pentachlorophenol induces inflammatory damage via the ATP2B4/Ca2+/ROS signaling axis in mouse testes
YZ
Yuxi Zhang
Beijing Tongren Hospital
RW
Ruoning Wu
Northeast Agricultural University
LC
Lidong Chao
Northeast Agricultural University
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Key Points
Inflammatory damage is observed in mouse testes due to sodium pentachlorophenol exposure, suggesting significant toxicity.
Key evidence shows that exposure increases reactive oxygen species levels and disrupts calcium signaling.
Assessment using a calcium signaling model highlights the ATP2B4/Ca2+/ROS axis in the inflammatory process.
Findings underscore the toxic implications of sodium pentachlorophenol, warranting further investigation into environmental effects.
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Zhang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76218c6e9836116a302bc
https://doi.org/https://doi.org/10.1016/j.pestbp.2026.107032
Sodium pentachlorophenol induces inflammatory damage via the ATP2B4/Ca2+/ROS signaling axis in mouse testes | Synapse