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Elevated asprosin expression exacerbates synovial inflammation by PPAR-γ-dependent mechanisms in rheumatoid arthritis | Synapse
March 3, 2026
Elevated asprosin expression exacerbates synovial inflammation by PPAR-γ-dependent mechanisms in rheumatoid arthritis
SX
Shu-Zhen Xu
ST
Sha-Sha Tao
Anhui Medical University
PW
Peng Wang
Kunming University of Science and Technology
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Key Points
Asprosin expression exacerbates synovial inflammation, indicating its role in disease progression.
Increased levels of asprosin correlate with heightened inflammatory markers in rheumatoid arthritis patients.
Assessment of asprosin's role reveals ppar-γ-dependent mechanisms contributing to inflammation.
Understanding asprosin's effects may enable new therapeutic strategies to manage rheumatoid arthritis.
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Xu et al. (Tue,) studied this question.
synapsesocial.com/papers/69a765f9badf0bb9e87db1c5
https://doi.org/https://doi.org/10.1016/j.clim.2026.110677
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