Recurrent retroperitoneal inflammatory myofibroblastic tumor in an elderly patient: Diagnostic pitfalls and implications for long-term follow-up

Key Points

Local recurrence of inflammatory myofibroblastic tumor occurred even after complete resection.
Histology identified ALK-negative tumor with a very low Ki-67 index, indicating low proliferation.
Multimodal imaging characterized a large hypervascular mass that resembled other tumors in the area.
Promotes the need for structured long-term imaging follow-up to detect potential recurrence of IMT.

Abstract

• Retroperitoneal inflammatory myofibroblastic tumor in an elderly patient is exceptionally rare and challenging. • Multimodal imaging revealed a large hypervascular mass mimicking other retroperitoneal soft-tissue tumors. • Histology showed ALK-negative IMT with very low Ki-67 (<1%), yet local recurrence occurred. • Even after complete resection, long-term structured imaging follow-up is essential to detect IMT recurrence.

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Yu et al. (Sun,) studied this question.

synapsesocial.com/papers/69a765febadf0bb9e87db31c https://doi.org/https://doi.org/10.1016/j.asjsur.2026.01.026

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