Quantitative assessment of the alignment between human trabecular microstructural orientation and mechanical anisotropy: Implications for Wolff's Law

Key Points

• Trabecular microstructural orientation aligns with mechanical anisotropy, indicating a strong relationship.
• Key evidence shows that increased alignment correlates significantly with mechanical properties across samples.
• Quantitative assessment of trabecular microstructure involved standard imaging techniques and mechanical testing methods.
• Implications for Wolff's Law suggest a deeper understanding of bone adaptation and strength under load.