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Digital twins for accelerating drug discovery and development: opportunities and challenges | Synapse
March 3, 2026
Digital twins for accelerating drug discovery and development: opportunities and challenges
MP
Matthew I. Peña
University of North Carolina at Chapel Hill
LC
Lindsay E. Clegg
AstraZeneca (Australia)
AN
Andrzej Nowojewski
AstraZeneca (United Kingdom)
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Key Points
Digital twins enhance drug discovery processes, potentially reducing time and costs associated with traditional methods.
A simulation-based framework enables real-time modeling of pharmacokinetics, improving drug efficacy predictions.
Observational analysis of current applications highlights both opportunities and challenges related to integration in clinical trials.
The findings underscore the need for further development in digital twin technologies for broader implementation in pharma.
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Peña et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7665dbadf0bb9e87dcb75
https://doi.org/https://doi.org/10.1016/j.drudis.2026.104617
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