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March 3, 2026
Cetylpyridinium chloride inhibits the polarization of tumor-associated macrophages and the proliferation of triple-negative breast cancer cells
GJ
Gaoyue Jiang
CL
Chunxia Li
BJ
Baihui Jia
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Key Points
Cetylpyridinium chloride inhibits the polarization of tumor-associated macrophages, subsequently reducing cancer cell proliferation.
The analysis shows a significant decrease in proliferative rates, particularly in triple-negative breast cancer cells.
Testing utilized both in vitro and in vivo models, focusing on cellular interactions and macrophage behavior.
The findings highlight the potential for cetylpyridinium chloride as a therapeutic option, although further studies are required.
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Jiang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7667cbadf0bb9e87dd340
https://doi.org/https://doi.org/10.1016/j.bbrc.2026.153389
Cetylpyridinium chloride inhibits the polarization of tumor-associated macrophages and the proliferation of triple-negative breast cancer cells | Synapse