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From Aortitis to Sweet’s: The Immune Spectrum of G-CSF Adverse Events | Synapse
March 3, 2026
From Aortitis to Sweet’s: The Immune Spectrum of G-CSF Adverse Events
AL
Aaron Lerner
Old Dominion University
CC
Cezar Augusto Muniz Caldas
Key Points
G-CSF is associated with a wide range of adverse events, particularly affecting immune responses.
Among the identified adverse events, aortitis and Sweet's syndrome are significant manifestations.
Analysis of clinical cases shows diverse inflammatory pathways linked to G-CSF administration in affected patients.
Understanding these immune responses may enhance clinical management and monitoring strategies for G-CSF therapy.
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Lerner et al. (Mon,) studied this question.
synapsesocial.com/papers/69a76687badf0bb9e87dd56f
https://doi.org/https://doi.org/10.1016/j.semarthrit.2026.152939