Developing a Mouse Model of Chronic Pseudomonas aeruginosa Skin Wound Infection

Key Points

• Chronic pseudomonas aeruginosa infection leads to significant bacterial burden in wounds, indicating the model's utility.
• Bioluminescence monitoring allows for precise tracking of infection progression over time, revealing insightful patterns of infection.
• The delayed inoculation method facilitates biofilm formation, promoting the chronicity of the infection in the wound model.
• Observational analysis using this mouse model highlights the importance of understanding chronic wound infections for treatment strategies.