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A superoxide anion-responsive supramolecular polymer from peptide-H2S donor conjugates for preventing liver ischemia-reperfusion injury | Synapse
March 3, 2026
A superoxide anion-responsive supramolecular polymer from peptide-H2S donor conjugates for preventing liver ischemia-reperfusion injury
YZ
Yanwen Zhang
Shanghai Innovative Research Center of Traditional Chinese Medicine
HX
Huiwen Xie
YS
Yiyang Shao
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Key Points
Superoxide anion-responsive supramolecular polymer shows promise for preventing liver ischemia-reperfusion injury.
A notable antioxidant capacity is indicated by experimental data on peptide-H2S donor conjugates.
Assessment utilizing conjugation strategies to create the supramolecular polymer proved effective against oxidative stress.
This innovative approach may enable new treatments for liver injury, with potential implications in clinical settings.
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Zhang et al. (Tue,) studied this question.
synapsesocial.com/papers/69a7669abadf0bb9e87ddaaa
https://doi.org/https://doi.org/10.1016/j.biomaterials.2026.124046