Double diabetes (DD) is a complex metabolic condition where characteristics of both type 1 diabetes (T1D) and type 2 diabetes (T2D) coexist. It typically presents in individuals with autoimmune diabetes who also display significant insulin resistance due to obesity or other metabolic factors. It is increasingly identified in young adults due to the global rise in obesity. This article describes the case of a 19-year-old female with obesity who presented with newly diagnosed diabetes, showing features of both T1D and T2D, focusing on diagnostic approaches, treatment strategies, and the critical role of healthy lifestyle interventions, including weight loss and the use of metformin. Laboratory investigations, clinical presentations, and treatment strategies are outlined to highlight the complexity of managing DD in adolescents.
Mickovski et al. (Sun,) studied this question.