Hypoxia-inducible factor signaling regulates embryonic interneuron development, GRIN2B expression and adult cortical function

Key Points

• Hypoxia-inducible factor signaling regulates interneuron development, impacting adult cortical function.
• A significant finding reveals that GRIN2B expression is influenced by these signaling pathways.
• Observational analysis of gene expression and signaling pathways highlights their role in brain development.
• These findings support the importance of hypoxia-inducible factor mechanisms in maintaining cortical health.