Low-molecular-weight fucoidan from Sargassum fusiforme alleviates H₂O₂-induced oxidative damage in in vitro and in vivo models

Key Points

• Alleviation of oxidative damage indicates a protective effect against cellular stress—a critical finding for potential therapies.
• In vitro tests revealed that low-molecular-weight fucoidan significantly reduces markers of oxidative stress caused by H₂O₂.
• Analysis included both in vitro and in vivo models to comprehensively assess the protective effects of fucoidan.
• This research highlights the potential of low-molecular-weight fucoidan as a therapeutic agent, needing further clinical evaluation.