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Membrane Remodeling Activity of Dengue Virus NS4A and NS1 Proteins: A Computational Perspective | Synapse
March 3, 2026
Membrane Remodeling Activity of Dengue Virus NS4A and NS1 Proteins: A Computational Perspective
DC
Dwaipayan Chaudhuri
KG
Kalyan Giri
Key Points
Dengue virus NS4A and NS1 proteins influence membrane remodeling activity, impacting viral replication.
Key observations showed structural variations in membrane interactions caused by NS4A and NS1 functionalities.
Computational modeling was utilized to analyze the dynamic behavior of these viral proteins interfacing with membranes.
Findings may enable targeted therapeutic strategies to inhibit dengue virus replication and improve treatment options.
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Chaudhuri et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76739badf0bb9e87e0136
https://doi.org/https://doi.org/10.1007/s00232-025-00369-w
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