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Methyl group dynamics and conformational flexibility in methacetin revealed by neutron spectroscopy | Synapse
March 3, 2026
Open Access
Methyl group dynamics and conformational flexibility in methacetin revealed by neutron spectroscopy
JP
Jose E.M. Pereira
EB
E. Boldyreva
BZ
Boris A. Zakharov
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Key Points
Conformational flexibility of methyl groups is crucial for understanding methacetin's behavior.
Analysis showed specific dynamic changes in molecular conformations upon exposure to different conditions.
Neutron spectroscopy allowed detailed observation of methyl group dynamics throughout the substance.
Findings highlight the significance of molecular dynamics in pharmaceutical applications.
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Pereira et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76752badf0bb9e87e078d
https://doi.org/https://doi.org/10.1016/j.molstruc.2026.145589