Adamantane tethered pyrazole carboxamides as antibacterial candidates: Synthesis, structural analysis and computational studies

Key Points

• Antibacterial activity was significantly enhanced in synthesized pyrazole carboxamides, highlighting their potential.
• Molecular docking revealed effective interactions with bacterial targets, providing insights into mechanism.
• Synthesis and structural analysis focused on adamantane tethered compounds to evaluate properties.
• Findings support further exploration of these compounds in developing new antibacterial agents.