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Distance- and hierarchy-dependent functional dysconnectivity in schizophrenia and its association with cortical microstructure | Synapse
March 3, 2026
Open Access
Distance- and hierarchy-dependent functional dysconnectivity in schizophrenia and its association with cortical microstructure
ID
Isaac David
University of Wisconsin System
SS
Shuntaro Sasai
University of Wisconsin–Madison
FP
Felipe Branco de Paiva
University of Helsinki
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Key Points
Functional dysconnectivity in schizophrenia correlates with alterations in cortical microstructure, affecting neural networks.
The study emphasizes distance and hierarchy dependencies within brain connectivity as critical factors.
Using advanced imaging techniques, the analysis assesses brain connectivity variations among subjects diagnosed with schizophrenia.
These findings suggest potential biomarkers for understanding schizophrenia's impact on brain structure and function.
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David et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76758badf0bb9e87e0901
https://doi.org/https://doi.org/10.1016/j.nicl.2026.103958