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Molecular pathology of primary aldosteronism and hypercortisolism: Impact on adrenal surgery | Synapse
March 3, 2026
Open Access
Molecular pathology of primary aldosteronism and hypercortisolism: Impact on adrenal surgery
TC
Tobias Carling
West Health
CS
Constantine A. Stratakis
National and Kapodistrian University of Athens
FF
Fábio R. Faucz
West Health
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Key Points
Molecular pathology plays a significant role in determining surgical outcomes in hypercortisolism.
Primary aldosteronism is linked to specific hormonal pathways that can complicate adrenal surgery.
Insights from the analysis may inform surgical strategies and improve patient management in adrenal disorders.
Understanding these molecular factors highlights the need for tailored approaches in adrenal surgery.
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Carling et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76775badf0bb9e87e0fb2
https://doi.org/https://doi.org/10.1016/j.isci.2026.114910
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