Efficacy and safety profiles of single versus multiple pipeline embolization devices for intracranial aneurysms: a systematic review and meta-analysis

Key Points

• Single pipeline embolization devices show similar efficacy to multiple devices in treating intracranial aneurysms, emphasizing possible treatment efficiency.
• The meta-analysis evaluated safety profiles, reporting negligible differences in complication rates between single and multiple devices across various studies.
• A systematic review of available literature encompassing multiple studies—enabling a robust comparison of device efficiency and safety profiles.
• Findings may enhance decision-making in clinical settings, but larger scale studies are encouraged to consolidate evidence on pipeline embolization devices.