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Sensory neurons shape local macrophage identity via TGF-β signaling | Synapse
March 3, 2026
Open Access
Sensory neurons shape local macrophage identity via TGF-β signaling
JK
Julia Kolter
University of Freiburg
CD
Clarissa-Laura Döring
SS
Samah Sarout
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Key Points
Sensory neurons play a vital role in defining macrophage identity, impacting immune responses significantly.
Key evidence shows that TGF-β signaling alters local macrophage characteristics, enhancing their function and interaction.
Assessment of neuroimmune interactions illustrates how sensory neurons influence immune cells through specific signaling pathways.
These findings emphasize the need for further exploration of neuroimmune communication and its implications for health.
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Kolter et al. (Tue,) studied this question.
synapsesocial.com/papers/69a76805badf0bb9e87e3490
https://doi.org/https://doi.org/10.5167/uzh-290690
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