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Injectable self-healing hydrogel loaded with a self-assembling LL-37 derivative for treating infected skin wounds | Synapse
March 3, 2026
Injectable self-healing hydrogel loaded with a self-assembling LL-37 derivative for treating infected skin wounds
QB
Qi Ba
JY
Jiaxin Yao
HT
Hao Tian
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Key Points
Wound healing is significantly accelerated with the self-healing hydrogel treatment, improving skin recovery.
Rats treated with the hydrogel showed a 30% faster healing rate over two weeks compared to controls.
Injectable self-healing hydrogel was developed with an LL-37 self-assembling derivative to enhance antibacterial properties.
Results indicate improved infection management and tissue regeneration in acute wound models, but further studies in humans are needed.
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Ba et al. (Thu,) studied this question.
synapsesocial.com/papers/69a76839badf0bb9e87e4024
https://doi.org/https://doi.org/10.1016/j.ijpharm.2026.126653