New thermodynamic aspects and speciation properties of the angiotensin-converting enzyme inhibitor drug, lisinopril with Cu2+, Zn2+, Ca2+, Mg2+ in sodium chloride aqueous solution
Key Points
Lisinopril shows significant interaction with metal ions Cu2+, Zn2+, Ca2+, and Mg2+ in sodium chloride solutions.
The thermodynamic analysis highlights the binding stability and speciation of lisinopril with these metal ions, crucial for its activation.
Evaluation through experimental methods reveals the effects of sodium chloride on the binding characteristics of lisinopril, enhancing understanding of its behavior.
These insights may aid in improving therapeutic strategies involving lisinopril, suggesting a need for further exploration in clinical settings.
Neue thermodynamische Aspekte und Spezifikationseigenschaften des Angiotensin-Converting-Enzym-Inhibitors Lisinopril mit Cu2+, Zn2+, Ca2+, Mg2+ in natriumchloridhaltiger wässriger Lösung | Synapse