Deciphering Persistent Prefrontal Cortex Kynurenic Acid Alterations and Molecular Shifts in Adult Mice Following Adolescent THC Exposure

Key Points

• Kynurenic acid levels in the prefrontal cortex significantly altered after THC exposure during adolescence.
• The research indicated that molecular shifts occur in adult mice due to early THC exposure, affecting brain function.
• Analysis of biochemical pathways demonstrates ongoing changes in neurotransmitter levels following adolescent THC exposure.
• These findings highlight potential long-term impacts of early THC on neurodevelopment and adult behavior.