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March 3, 2026
Open Access
Gemini surfactant-stabilized cubosomes for enhanced topical delivery of 5-fluorouracil in cutaneous squamous cell carcinoma
RR
Ruchira Raychaudhuri
Manipal Academy of Higher Education
AN
Ajinkya Nitin Nikam
Manipal Academy of Higher Education
NJ
Naitik Jain
Manipal Academy of Higher Education
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Key Points
Enhanced delivery efficiency of 5-fluorouracil with gemini surfactant-stabilized cubosomes was observed.
A significant improvement in local drug concentration was achieved, indicating effective treatment for skin cancer.
Assessment involved innovative formulation tactics using cubosomes as delivery systems.
May enable greater therapeutic effects in skin cancer treatments while minimizing systemic side effects.
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Raychaudhuri et al. (Fri,) studied this question.
synapsesocial.com/papers/69a7688fbadf0bb9e87e51c1
https://doi.org/https://doi.org/10.1016/j.ijpx.2026.100504
Gemini surfactant-stabilized cubosomes for enhanced topical delivery of 5-fluorouracil in cutaneous squamous cell carcinoma | Synapse