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Pannexin 1a regulates visual system development and ocular integrity in zebrafish | Synapse
March 3, 2026
Open Access
Pannexin 1a regulates visual system development and ocular integrity in zebrafish
SS
Shiva Sabour
SH
Sarah Houshangi-Tabrizi
GZ
Georg S.O. Zoidl
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Key Points
Visual system development is influenced by pannexin 1a signaling pathways, impacting ocular integrity.
Key evidence reveals alterations in ocular structure and function when pannexin 1a is disrupted during development.
Analysis of genetic modifications in zebrafish demonstrates the importance of pannexin 1a for healthy visual pathways.
Findings highlight the potential for understanding eye development, but further studies are needed to confirm these effects in other models.
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Sabour et al. (Fri,) studied this question.
synapsesocial.com/papers/69a768a9badf0bb9e87e57f5
https://doi.org/https://doi.org/10.1016/j.isci.2026.114925
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