Molecular heterogeneity of Glioblastoma-associated microglia and macrophages and myeloid-derived suppressor cells: Insights from single-cell omics and therapeutic implications
Key Points
Heterogeneity in glioblastoma-associated myeloid cells indicates diverse molecular profiles and potential functional roles.
The findings highlight the importance of microglia and myeloid-derived suppressor cells in glioblastoma progression and treatment.
Assessment using single-cell omics provides insights into cellular interactions and variations within glioblastoma microenvironment.
The implications stress the need for tailored therapies targeting specific myeloid cell subtypes to improve patient outcomes.
Molecular heterogeneity of Glioblastoma-associated microglia and macrophages and myeloid-derived suppressor cells: Insights from single-cell omics and therapeutic implications | Synapse