Regular nephrology follow-up reduced all-cause mortality by 35–45% (HR 0.55–0.65) compared to irregular follow-up in adults with CKD stages 3-5.
Does regular nephrology follow-up improve clinical outcomes in adults with chronic kidney disease (stages 3-5)?
Regular nephrology follow-up in patients with CKD stages 3-5 is associated with significantly lower mortality, slower disease progression, and fewer cardiovascular complications compared to irregular follow-up.
Effect estimate: HR 0.55–0.65
Absolute Event Rate: 6% vs 12%
Abstract Chronic kidney disease (CKD) is a progressive condition associated with substantial morbidity, mortality, and healthcare burden. Regular nephrology follow‑up is recommended by international guidelines to slow disease progression, optimize therapy, and prevent complications. However, adherence to scheduled visits varies widely. This narrative review examines the impact of regular versus irregular follow‑up on renal outcomes, cardiovascular events, hospitalization rates, mortality, and patient‑reported outcomes. Evidence consistently shows that regular follow‑up is associated with slower CKD progression, fewer cardiovascular complications, reduced unplanned hospitalizations, improved dialysis preparedness, and lower mortality. These findings underscore the importance of structured, continuous nephrology care and highlight the need for interventions to improve follow‑up adherence.
Duranti Ennio (Thu,) conducted a review in Adults with chronic kidney disease stages 3-5 undergoing regular versus irregular nephrology follow-up. Regular nephrology follow-up vs. Irregular or absent nephrology follow-up was evaluated on All-cause mortality (HR 0.55–0.65). Regular nephrology follow-up reduced all-cause mortality by 35–45% (HR 0.55–0.65) compared to irregular follow-up in adults with CKD stages 3-5.