Evaluation of Mean Platelet Volume and Platelet Distribution Width as an Early Marker of Neonatal Sepsis: A Case–Control Study

Key Points

• The aim is to assess the effectiveness of MPV and PDW as early indicators of neonatal sepsis and their predictive value for mortality.
• Case-control design
• Comparison of MPV and PDW levels in neonates with and without sepsis
• Analysis of data from term and preterm infants
• MPV is significantly higher in neonates with sepsis compared to those without.
• PDW is also elevated in sepsis cases but is less predictive than MPV.
• Both MPV and PDW show potential as surrogate markers for neonatal sepsis.