Efficacy, Comparative Effectiveness, and Harm of Respiratory Syncytial Virus Vaccines in Adults Who Are Not Pregnant or Immunocompromised: A Rapid Review for the American College of Physicians

Key Points

• This review aims to evaluate the efficacy and comparative effectiveness of respiratory syncytial virus vaccines in adults who are not pregnant or immunocompromised.
• Conducted a rapid review to gather existing data on vaccine efficacy
• Focused on adult populations who are not pregnant or immunocompromised
• Reviewed comparative effectiveness against other respiratory viruses
• Identified varying levels of efficacy among different vaccine candidates
• Highlighted potential safety concerns for certain vaccine options
• Found evidence suggesting improved outcomes in vaccinated adults