Trichosporon asahii is an opportunistic yeast that colonizes the skin and mucous membranes but may cause severe invasive infections in critically ill patients. We report the case of an 81-year old man with extensive second- and third degree thermal burns (30-39% total body surface area) who, during the third week of intensive care, developed a deep infection of a previously amputated femoral stump. Cultures repeatedly yielded multidrug-resistant Pseudomonas aeruginosa and T. asahii, identified by MALDI-TOF mass spectrometry. Combined surgical management and antimicrobial therapy with meropenem and posaconazole led to clinical resolution and a favourable outcome.
Martinez-Mafla et al. (Tue,) studied this question.