Long-Term Outcomes and Natural Course of Giant Cerebral Arteriovenous Malformations (> 6 cm): Insights From a National Multicenter Propensity Score-Matched Cohort.

Key Points

• This research aims to evaluate the long-term outcomes and natural progression of giant cerebral arteriovenous malformations (AVMs) larger than 6 cm.
• Analyzed a national multicenter cohort of patients with giant AVMs.
• Performed propensity score matching to compare interventional treatments and conservative management.
• Evaluated annual rupture rates and risks of neurological deterioration.
• Annual rupture rate of giant AVMs is approximately 3.6%.
• Interventional treatment shows no significant benefit over conservative management.
• Substantial risks of hemorrhagic stroke and neurological decline persist for certain AVM types.

Abstract