Characterisation of the Novel HLA-B*39:239N Allele by Sequencing-Based Typing.

Key Points

• The research aims to identify and characterize the novel HLA-B*39:239N allele through precise genetic sequencing.
• Conducted sequencing-based typing of HLA-B alleles
• Focused on exon 2 and codon 44 variations
• Compared HLA-B*39:239N with HLA-B*39:01:01:05
• Identified a single nucleotide deletion at codon 44 in HLA-B*39:239N
• Demonstrated that HLA-B*39:239N is distinct from HLA-B*39:01:01:05