Immunoassay antibody modification significantly impacts low-dose dexamethasone suppression test cutoffs in dogs with Cushing syndrome

Key Points

• The study aims to evaluate how modifications in immunoassay antibodies affect dexamethasone suppression test cutoff values in dogs with Cushing syndrome.
• Assessment of T8 cortisol levels using modified immunoassay antibodies
• Comparison of new and traditional cutoff values for diagnosis
• Analysis of Cushing syndrome in canine subjects
• New cutoff value for T8 cortisol was successfully identified
• Modified antibody usage improved diagnostic accuracy
• Implications for more precise diagnosis of Cushing syndrome in dogs