Schlafen 11 (SLFN11) And Tumor-Infiltrating Lymphocytes (TILs): Dual Predictive Biomarkers In Ovarian Serous Carcinoma

Key Points

• To evaluate SLFN11 and TIL density as predictive biomarkers for response to chemotherapy and survival in ovarian serous carcinoma.
• Conducted immunohistochemical analysis of SLFN11 expression
• Assessed the density of tumor-infiltrating lymphocytes
• Analyzed the relationship with chemotherapy response and survival outcomes
• Higher SLFN11 expression correlates with better chemotherapy response
• Increased TIL density is associated with improved survival rates
• Both biomarkers may aid in developing personalized treatment strategies