Validation of the Systemic Lupus Erythematosus Disease Activity Score (SLE-DAS) in a Chinese Cohort: Comparison with SLEDAI-2-K

Key Points

• The study aims to validate the SLE-DAS for assessing disease activity in systemic lupus erythematosus compared to SLEDAI-2-K.
• Comparison of SLE-DAS and SLEDAI-2-K scores in a Chinese cohort
• Assessment of nephritis and hematological manifestations
• Analysis of baseline scores relative to organ damage
• SLE-DAS showed superior accuracy over SLEDAI-2-K in assessing disease activity
• Baseline SLE-DAS positively associated with short-term organ damage accrual
• Need for long-term validation of findings noted