Fecal calprotectin is an accurate noninvasive screening tool for pouchitis | Synapse
March 12, 2026
Fecal calprotectin is an accurate noninvasive screening tool for pouchitis
Key Points
The aim is to evaluate fecal calprotectin as a noninvasive method for detecting pouchitis.
Assessment of fecal calprotectin levels in patients with pouchitis
Determination of thresholds for normal and inflamed pouches
Comparison of fecal calprotectin with endoscopic evaluations
Threshold of 167 µg/g accurately identifies normal from inflamed pouches
Threshold of 280 µg/g differentiates mild from severe endoscopic disease
Fecal calprotectin provides reliable results for pouch inflammation grading
Abstract
FC is accurate for detecting and grading pouch inflammation. Thresholds near 167 and 280 µg/g reliably discriminate normal from inflamed pouches and mild from severe endoscopic disease, respectively.