New onset seizure etiologies and outcomes among adults with HIV in the era of broadly available antiretroviral therapies

Key Points

• To investigate the causes and outcomes of new onset seizures among adults living with HIV in the context of available antiretroviral therapy.
• Cohort study of rural adults living with HIV
• Assessment of seizure types and causes
• Follow-up evaluation for morbidity and mortality
• 37% mortality during follow-up
• 24% developed epilepsy
• Opportunistic infections were the most common seizure cause
• Prior central nervous system injury increased epilepsy risk