Intrauterine devices incorporating nanocarriers for targeted cervical cancer therapy

Key Points

• This research aims to evaluate the effectiveness of polyethylene-based drug-loaded intrauterine devices for treating cervical cancer.
• Utilized polyethylene-based materials to fabricate drug-loaded intrauterine devices (IUDs).
• Assessed manufacturing reproducibility of these devices.
• Conducted sustained drug release studies to evaluate effectiveness over time.
• Tested for cytotoxic and antimicrobial activity against cancer cells.
• IUDs displayed consistent manufacturing quality across repetitions.
• Achieved sustained drug release suitable for therapy.
• Demonstrated promising cytotoxic effects on cervical cancer cells.
• Showed significant antimicrobial activity, adding to therapeutic potential.