Objective: The aim of this study was to provide information on the demographic characteristics and laboratory parameters of primary glomerulonephritis (PGN) patients diagnosed at our center and to determine the epidemiology of PGN in our region.Method: 148 adult PGN cases diagnosed via percutaneous renal biopsy at our hospital were included in the study. Patients whose biopsy specimens could not be analyzed with immunofluorescence, those reported as non-diagnostic, those with a history of kidney transplantation who underwent biopsy, those who underwent biopsy with a presumptive diagnosis of malignancy, and those whose tests were unavailable were excluded from the study.Results: The overall mean age of the patients was 38.5±12.9 years. 50% of the patients were female and 50% were male. Our study found that biopsies were performed for nephrotic syndrome (70.3%), asymptomatic urinary abnormalities (21.6%), and acute nephritic syndrome (8.1%) in both genders and all age groups. The most common PGN subtypes were FSGS (41.2%) and MGN (18.9%), respectively. Following these, the following were IgAN (15.5%), MPGN (14.2%), RPGN (5.4%), and MCD (4.7%). FSGS was the most common PGN subtype in patients younger than 60 years of age, and MGN in patients older than 60 years. MGN was found to be the PGN subtype with the highest mean proteinuria.Conclusion: This is the first study to investigate the distribution, demographic characteristics, and laboratory parameters of primary glomerulonephritis in the Southeastern Anatolia Region and provides information about the PGN epidemiology in our region. The data obtained in our study were consistent with many studies conducted in our country and around the world.
Öngören et al. (Tue,) studied this question.